Amoxicillin - pharmacology
Today Amoxicillin for sale is available even without prescription. So, deciding to order medication and conduct home therapy, read carefully pharmacological effect of this drug.
Pharmacological effect: Amoxicillin is an antibiotic of a large area of use belonging to a group of cyborg penicillins. Amoxicillin has a very quick effect. The mechanism of drug action is inhibition of cell wall synthesis, as with other antibiotics, penicillin-owned group.
The drug has antimicrobial action and is effective against gram-positive microorganisms (staphylococci, streptococci, streptococci groups A, B, C, G, H, I, M); gram-negative microorganisms (Neisseria meningitidis, N. gonorrhoeae); gram-negative microbes (Escherichia coli, Shigella, Klebsiella spp., Salmonella, Campilobacter, Bordetella pertussis, chlamydia, and others).
Amoxicillin is effective against all bacteria, not resistant to penicillin G: Corynebacterium, bacilli, Actinomycetes, streptobatsillam, Spirillium minus, Listeria, Spirochaeta, and others, as well as various anaerobic bacteria.
The drug is not sensitive to acidic conditions and therefore active when taken orally.
Pharmacodynamic of Amoxicillin: When internal use of the drug it is almost completely absorbed by the mucous of the gastrointestinal tract. Food intake has no effect on the degree of absorption of the drug. The limiting concentration of the drug is observed in plasma after 1-2 hours after the internal use and is approximately 7-8 mg / ml. Binding to plasma proteins happens in 20%. The drug penetrates well into tissues and body fluids: high degree of concentration observed in the lungs, kidneys, mucous membranes of respiratory system, urine, plasma.
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